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Journal
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Medizin
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人子宫平滑肌的收缩力测量对药物开发的帮助
JoVE Journal
Medizin
This content is Free Access.
JoVE Journal
Medizin
Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development
Please note that all translations are automatically generated.
Click here for the English version.
人子宫平滑肌的收缩力测量对药物开发的帮助
DOI:
10.3791/56639-v
•
07:56 min
•
January 26, 2018
•
Sarah Arrowsmith*
1
,
Peter Keov
,
Markus Muttenthaler
4
,
Christian W. Gruber*
2,5
1
Harris-Wellbeing Preterm Birth Research Centre, Department of Cellular and Molecular Physiology, Institute of Translational Medicine
,
University of Liverpool
,
2
School of Biomedical Sciences
,
The University of Queensland
,
3
Faculty of Chemistry, Institute of Biological Chemistry
,
University of Vienna
,
4
Institute for Molecular Bioscience
,
University of Queensland
,
5
Center for Physiology and Pharmacology
,
Medical University of Vienna
Kapitel
00:05
Titel
00:49
Tissue Preparation and Strip Dissection
03:00
Tissue Mounting
04:06
Myometrial Contraction Analysis
05:28
Results: Representative Effects and Receptor Selectivity of a Novel Compound in Human Myometrial Contraction
06:41
Conclusion
Summary
Automatische Übersetzung
English (Original)
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français (French)
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Automatische Übersetzung
本文介绍了研究人类肌的
活体
收缩的实验方案及其在药物发现中的应用
.
这项技术是用来提高对层生理学和病理生理学的理解, 以及验证药理数据从新的研究探针或药物的线索。
Tags
Contractility Measurements
Human Uterine Smooth Muscle
Drug Development
Myometrial Physiology
Preterm Birth
Dysfunctional Labor
Peristaltic Pump
Physiological Saline
Muscle Strips
Force Transducer
Article
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