/
/
Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death
Zum Anzeigen dieser Inhalte ist ein JoVE-Abonnement erforderlich. Melden Sie sich an oder starten Sie Ihre kostenlose Testversion.
Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death
9,092 Views
•
08:26 min
•
October 31, 2017
DOI:
Summary
Automatically generated
We illustrate a straight-forward method to derive murine primary macrophages from bone marrow cells and a simple method to prepare BSA-fatty acid conjugates. Then we demonstrate that saturated fatty acids can induce macrophage cell death, and such cell death is positively associated with cellular accumulation of ceramide levels.
Read Article
Cite this Article
Zhang, Y., Hao, J., Sun, Y., Li, B. Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death. J. Vis. Exp. (128), e56535, doi:10.3791/56535 (2017).
Copy