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Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS
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Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS

Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS

8,364 Views

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09:20 min

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August 10, 2017

DOI:

10.3791/55878-v

DOI:
10.3791/55878-v

•

09:20 min
August 10, 2017

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2 Views
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1Section des Sciences Pharmaceutiques,Universités des Geneva–Lausanne (EPGL)

Tags

HDAC1HDAC6HeLa CellsUHPLC-MSHDAC InhibitorSelectivityDrug DiscoverySimultaneous MeasurementCell-based AssayAcetylationTrichostatin AMS275Tubastatin A

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Simões-Pires, C. A., Zwick, V., Cretton, S., Cuendet, M. Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS. J. Vis. Exp. (126), e55878, doi:10.3791/55878 (2017).

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