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Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products
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JoVE Journal Chemie
Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products

Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products

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09:24 min

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August 22, 2017

DOI:

10.3791/55850-v

DOI:
10.3791/55850-v

•

09:24 min
August 22, 2017

•

2 Views
, , , , , ,
1Department of Attribute Sciences,Amgen, Inc., 2Small Molecule Pharmaceutical Sciences,Genentech, Inc., 3NMR Service + Consulting, 4Mestrelab Research

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19F NMRNon-destructive AnalysisDrug ContentPharmaceuticalsFormulationCalibrationT1 Relaxation TimeAPIRINMR Software

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Silva Elipe, M. V., Li, L., Nagapudi, K., Kook, A. M., Cobas, C., Iglesias, I., Peng, C. Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products. J. Vis. Exp. (126), e55850, doi:10.3791/55850 (2017).

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