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An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach
JoVE Journal
Neurowissenschaften
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JoVE Journal Neurowissenschaften
An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach
DOI:

07:13 min

December 07, 2016

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Kapitel

  • 00:05Titel
  • 00:50Injection Site Preparation
  • 02:41Sclerotomy and Subretinal Injection
  • 04:40Results: Retinal Structure Was Assessed Using OCT Imaging
  • 06:29Conclusion

Summary

Automatische Übersetzung

Subretinal injections are the most common technique for delivering large therapeutic agents such as proteins and viral vectors to photoreceptors and the retinal pigment epithelium. An alternative method in mice that successfully targets the subretinal space with minimal collateral damage and fast recovery times is described here.

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