This study presents an innovative running wheel-based animal mobility system to quantify an effective exercise activity in rats. A rat-friendly testbed is built, using a predefined adaptive acceleration curve, and a high correlation between the effective exercise rate and the infarct volume suggests the protocol's potential for stroke prevention experiments.
Chen, C., Yang, C., Chang, C. An Innovative Running Wheel-based Mechanism for Improved Rat Training Performance. J. Vis. Exp. (115), e54354, doi:10.3791/54354 (2016).