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大人の皮膚線維芽細胞からのインスリン分泌細胞を得るために安全かつ簡便な方法として、エピジェネティック変換
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March 18, 2016
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Summary
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Here, a new method that allows the conversion of adult skin fibroblasts into insulin-secreting cells is presented. This technique is based on epigenetic conversion, does not involve the use of retroviral vectors nor the acquisition of a stable pluripotent state. It is therefore highly promising for translational medicine applications.
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Brevini, T. A., Pennarossa, G., Maffei, S., Zenobi, A., Gandolfi, F. Epigenetic Conversion as a Safe and Simple Method to Obtain Insulin-secreting Cells from Adult Skin Fibroblasts. J. Vis. Exp. (109), e53880, doi:10.3791/53880 (2016).
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