Journal
/
Chemie
/
Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
JoVE Journal
Chemie
Zum Anzeigen dieser Inhalte ist ein JoVE-Abonnement erforderlich.  Melden Sie sich an oder starten Sie Ihre kostenlose Testversion.
JoVE Journal Chemie
Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles

DOI:
10.3791/53047-v

•

07:32 min

•

August 28, 2015

•

, , , ,
1School of Pharmacy,Pacific University, 2Department of Pharmaceutical Sciences, College of Pharmacy,Oregon State University

Kapitel

  • 00:05Titel
  • 01:42Preparation of Individual and Multi-drug Loaded Micelles by Solvent Casting Method
  • 02:56Assessment of Drug Loading and Stability in Micelles Using Reverse-phase High Performance Liquid Chromatography
  • 03:52Assessment of Micelle Particle Size by Dynamic Light Scattering
  • 04:29Assessment of In Vitro Drug Release from Individual Micelles and Dual Drug Micelles
  • 05:21Results: Preparation and Characterization of Poorly Water Soluble Drugs in Micelles
  • 06:29Conclusion

Summary

Automatische Übersetzung

Automatische Übersetzung

The goal of this protocol is to describe the preparation and characterization of physically entrapped, poorly water soluble drugs in micellar drug delivery systems composed of amphiphilic block copolymers.

Tags

Polymeric MicellesPEG-b-PLADocetaxelEverolimusSolvent CastingDrug LoadingDrug StabilityDrug ReleaseDynamic Light ScatteringCharacterization

Article

Embed

ZUR WIEDERGABELISTE HINZUFÜGEN

Usage Statistics

Verwandte Videos

Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Preparation and Characterization of SDF-1α-Chitosan-Dextran Sulfate Nanoparticles

Synthesis and Characterization of Supramolecular Colloids

Low-energy Cathodoluminescence for (Oxy)Nitride Phosphors

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions

Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level

Synthesis of Plant Phenol-derived Polymeric Dyes for Direct or Mordant-based Hair Dyeing

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Preparation and Characterization of C60/Graphene Hybrid Nanostructures

Read Article