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Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
 

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings

Article DOI: 10.3791/52581-v 14:41 min October 25th, 2015
October 25th, 2015

Kapitel

Summary

The chronically instrumented non-anesthetized fetal sheep model is used to study human fetal development in health and disease, because it permits surgical placement and maintenance of catheters and electrodes, repetitive blood sampling, substance injection, recording of bioelectrical activity, and in vivo imaging. We describe the procedures required to establish this model.

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Keywords: Fetal Sheep Chronic Instrumentation Multivariate Recordings Non-anesthetized Fetal Development Pathophysiologic Stimuli Glucocorticoid Treatment Therapeutic Hypothermia Catheter Placement Bioelectrical Activity In Vivo Organ Imaging
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