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La bioconjugaison et radiosynthèse de<sup> 89</sup> Anticorps Zr-DFO-étiquetés
JoVE Journal
Chemie
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JoVE Journal Chemie
The Bioconjugation and Radiosynthesis of 89Zr-DFO-labeled Antibodies

La bioconjugaison et radiosynthèse de<sup> 89</sup> Anticorps Zr-DFO-étiquetés

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09:29 min

February 12, 2015

DOI:

09:29 min
February 12, 2015

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Summary

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Due to its multi-day radioactive half-life and favorable decay properties, the positron-emitting radiometal 89Zr is extremely well-suited for use in antibody-based radiopharmaceuticals for PET imaging. In this protocol, the bioconjugation, radiosynthesis, and preclinical application of 89Zr-labeled antibodies will be described.

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