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Measuring Spinal Presynaptic Inhibition in Mice By Dorsal Root Potential Recording In Vivo
JoVE Journal
Neurowissenschaften
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JoVE Journal Neurowissenschaften
Measuring Spinal Presynaptic Inhibition in Mice By Dorsal Root Potential Recording In Vivo

Measuring Spinal Presynaptic Inhibition in Mice By Dorsal Root Potential Recording In Vivo

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09:48 min

March 29, 2014

DOI:

09:48 min
March 29, 2014

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Summary

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GABAergic presynaptic inhibition is a powerful inhibitory mechanism in the spinal cord important for motor and sensory signal integration in spinal cord networks. Underlying primary afferent depolarization can be measured by recording of dorsal root potentials (DRP). Here we demonstrate a method of in vivo recording of DRP in mice.

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