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Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
JoVE Journal
Medizin
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JoVE Journal Medizin
Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

20,347 Views

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05:58 min

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September 11, 2013

DOI:

10.3791/50660-v

DOI:
10.3791/50660-v

•

05:58 min
September 11, 2013

•

7 Views
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1Retina Service, Angiogenesis Laboratory, Department of Ophthalmology,Massachusetts Eye and Ear Infirmary, Harvard Medical School

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Creating experimental retinal detachments with a reproducible and sustained height of detachment, and without subretinal hemorrhage, is important for studying the pathophysiology of photoreceptor cell loss in retinal disease and evaluating potential therapeutic interventions. Here, we report such a method in detail.

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Matsumoto, H., Miller, J. W., Vavvas, D. G. Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate. J. Vis. Exp. (79), e50660, doi:10.3791/50660 (2013).

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