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Avidity-based Extracellular Interaction Screening (AVEXIS) for the Scalable Detection of Low-affinity Extracellular Receptor-Ligand Interactions

JoVE Journal
Biologie

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JoVE Journal Biologie

Avidity-based Extracellular Interaction Screening (AVEXIS) for the Scalable Detection of Low-affinity Extracellular Receptor-Ligand Interactions

Avidity-based Extracellular Interaction Screening (AVEXIS) for the Scalable Detection of Low-affinity Extracellular Receptor-Ligand Interactions

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12:30 min

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March 05, 2012

DOI:

DOI:

•

12:30 min

March 05, 2012

•

3 Views

Jason S. Kerr, Gavin J. Wright

¹Cell Surface Signalling Laboratory,Wellcome Trust Sanger Institute

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Avidity-based Extracellular Interaction Screening AVEXIS Low-affinity Interactions Extracellular Receptor-ligand Interactions Intercellular Communication Multicellular Organisms Protein-protein Interactions Binding Partner Membrane-embedded Proteins Posttranslational Modifications Interaction Affinities High Throughput Methods AVEXIS Assay Weak Protein Interactions False Positive Rate High Throughput Format Recombinant Protein Libraries

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