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Investigating HFpEF Pathophysiology in a Hyperlipidemia-Induced Mouse Model

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Inducing Hyperlipidemia to Characterize Diastolic Dysfunction in HFpEF Mice

JoVE Journal
Medizin

This content is Free Access.

JoVE Journal Medizin

Inducing Hyperlipidemia to Characterize Diastolic Dysfunction in HFpEF Mice

Inducing Hyperlipidemia to Characterize Diastolic Dysfunction in HFpEF Mice

Investigating HFpEF Pathophysiology in a Hyperlipidemia-Induced Mouse Model

DOI:

10.3791/201537-v

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01:48 min

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March 29, 2024

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Monique Williams², Ali Kamiar³, Jose Manuel Condor Capcha², Monica Anne Rasmussen, Qusai Alitter, Rosemeire Kanashiro Takeuchi³, Lauro Mitsuru Takeuchi, Joshua M. Hare², Lina A. Shehadeh²

¹Department of Medicine, Division of Cardiology,University of Miami Leonard M. Miller School of Medicine, ²Interdisciplinary Stem Cell Institute,University of Miami Leonard M. Miller School of Medicine, ³Department of Molecular and Cellular Pharmacology,University of Miami Leonard M. Miller School of Medicine, ⁴Department of Medical Education,University of Miami Leonard M. Miller School of Medicine

Tags

Hyperlipidemia HFpEF Viral Vector AAV Tail Vein Injection Poloxamer 407 Peritoneal Injection Echocardiography Diastolic Dysfunction Mitral Flow Velocity Mitral Annular Velocity

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