Chapter 7
Skeletal Muscle Relaxants
![Neuromuscular Junction And Blockade](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14483.jpg)
The site of chemical communication between a motor neuron and a muscle fiber is called the neuromuscular junction (NMJ). The end of the motor neuron…
![Classification of Skeletal Muscle Relaxants](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14484.jpg)
Skeletal muscle relaxants are a group of drugs that can reduce muscle stiffness and induce temporary paralysis to relieve pain. These agents can act…
![Nondepolarizing (Competitive) Neuromuscular Blockers: Pharmacological Actions](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14486.jpg)
Nondepolarizing neuromuscular blockers prevent the membrane depolarization of muscle cells and inhibit muscle contraction. These are usually…
![Nondepolarizing (Competitive) Neuromuscular Blockers: Pharmacokinetics](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14487.jpg)
All neuromuscular blocking agents are injected intravenously because they are poorly absorbed from the GI tract. Rapid onset is achieved with…
![Depolarizing Blockers: Pharmocokinetics](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14489.jpg)
Depolarizing blockers are administered through intravenous injection. Succinylcholine is the most common choice of depolarizing blockers in emergency…
![Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14490.jpg)
Directly acting muscle relaxants like dantrolene and botulinum toxin (BoNT) have distinct mechanisms and applications. Dantrolene, a hydantoin…
![Skeletal Muscle Relaxants: Therapeutic Uses](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14492.jpg)
Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants…
![Spasmolytic Agents: Chemical Classification](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14493.jpg)
Spasmolytic agents are drugs used to alleviate muscle spasms and spasticity. They can be categorized into different chemical groups based on their…
![Visualizing the Live <em>Drosophila</em> Glial-neuromuscular Junction with Fluorescent Dyes](https://jovecdn2.ccindex.cn/files/thumbs/1154_t.png)
Our project identified GFP labeled glial structures at the developing larval fly neuromuscular synapse. To look at development of live…
![Measuring Neuromuscular Junction Functionality](https://jovecdn2.ccindex.cn/files/thumbs/55227_t.png)
Neuromuscular junction (NMJ) functionality plays a pivotal role when studying diseases in which the communication between motor neuron and muscle is…