Wanqiu Chen Division of Regenerative Medicine, Department of Medicine Loma Linda University Biography Publications Institution JoVE Articles Wanqiu Chen has not added a biography. If you are Wanqiu Chen and would like to personalize this page please email our Author Liaison for assistance. Publications Different Effects of SgRNA Length on CRISPR-mediated Gene Knockout Efficiency Scientific Reports. Jun, 2016 | Pubmed ID: 27338021 Generation of Mesenchymal Stem Cells by Blood Cell Reprogramming Current Stem Cell Research & Therapy. 2016 | Pubmed ID: 26027679 PDGFB-based Stem Cell Gene Therapy Increases Bone Strength in the Mouse Proceedings of the National Academy of Sciences of the United States of America. Jul, 2015 | Pubmed ID: 26150503 Brain Arteriovenous Malformation Modeling, Pathogenesis, and Novel Therapeutic Targets Translational Stroke Research. Jun, 2014 | Pubmed ID: 24723256 Novel Brain Arteriovenous Malformation Mouse Models for Type 1 Hereditary Hemorrhagic Telangiectasia PloS One. 2014 | Pubmed ID: 24520391 Induction of Brain Arteriovenous Malformation in the Adult Mouse Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24510874 De Novo Cerebrovascular Malformation in the Adult Mouse After Endothelial Alk1 Deletion and Angiogenic Stimulation Stroke. Mar, 2014 | Pubmed ID: 24457293 Reduced Mural Cell Coverage and Impaired Vessel Integrity After Angiogenic Stimulation in the Alk1-deficient Brain Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2013 | Pubmed ID: 23241407 Preoperative Mucosal Tolerance to Brain Antigens and a Neuroprotective Immune Response Following Surgical Brain Injury Journal of Neurosurgery. Jan, 2012 | Pubmed ID: 22017304 Hydrogen is Neuroprotective Against Surgically Induced Brain Injury Medical Gas Research. 2011 | Pubmed ID: 22146427 Granulocyte Colony-stimulating Factor Treatment Provides Neuroprotection in Surgically Induced Brain Injured Mice Acta Neurochirurgica. Supplement. 2011 | Pubmed ID: 21725766 Pretreatment with Normobaric and Hyperbaric Oxygenation Worsens Cerebral Edema and Neurologic Outcomes in a Murine Model of Surgically Induced Brain Injury Acta Neurochirurgica. Supplement. 2011 | Pubmed ID: 21725763 Effects of Recombinant Osteopontin on Blood-brain Barrier Disruption After Subarachnoid Hemorrhage in Rats Acta Neurochirurgica. Supplement. 2011 | Pubmed ID: 21725761 Endothelin Receptor-A (ETa) Inhibition Fails to Improve Neonatal Hypoxic-ischemic Brain Injury in Rats Acta Neurochirurgica. Supplement. 2011 | Pubmed ID: 21725757 Subarachnoid Hemorrhage Causes Pulmonary Endothelial Cell Apoptosis and Neurogenic Pulmonary Edema in Mice Acta Neurochirurgica. Supplement. 2011 | Pubmed ID: 21725743 Arteriovenous Malformation in the Adult Mouse Brain Resembling the Human Disease Annals of Neurology. Jun, 2011 | Pubmed ID: 21437931 Osteopontin Reduced Hypoxia-ischemia Neonatal Brain Injury by Suppression of Apoptosis in a Rat Pup Model Stroke; a Journal of Cerebral Circulation. Mar, 2011 | Pubmed ID: 21273567 Mechanisms of Statin Treatment in Cerebral Vasospasm Acta Neurochirurgica. Supplement. 2011 | Pubmed ID: 21125437 Role of Osteopontin in Early Brain Injury After Subarachnoid Hemorrhage in Rats Acta Neurochirurgica. Supplement. 2011 | Pubmed ID: 21116919 Vascular Adhesion Protein-1 Inhibition Provides Antiinflammatory Protection After an Intracerebral Hemorrhagic Stroke in Mice Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Mar, 2011 | Pubmed ID: 20877383 Recombinant Osteopontin in Cerebral Vasospasm After Subarachnoid Hemorrhage Annals of Neurology. Nov, 2010 | Pubmed ID: 21031580 Ac-YVAD-CMK Decreases Blood-Brain Barrier Degradation by Inhibiting Caspase-1 Activation of Interleukin-1β in Intracerebral Hemorrhage Mouse Model Translational Stroke Research. Mar, 2010 | Pubmed ID: 20596246 Protective Effect of Melatonin Upon Neuropathology, Striatal Function, and Memory Ability After Intracerebral Hemorrhage in Rats Journal of Neurotrauma. Mar, 2010 | Pubmed ID: 20350200 Role of Gap Junctions in Early Brain Injury Following Subarachnoid Hemorrhage Brain Research. Feb, 2010 | Pubmed ID: 20018179 Maternal Hypoxia Increases the Activity of MMPs and Decreases the Expression of TIMPs in the Brain of Neonatal Rats Developmental Neurobiology. Feb, 2010 | Pubmed ID: 20017119 Protective Effects of Recombinant Osteopontin on Early Brain Injury After Subarachnoid Hemorrhage in Rats Critical Care Medicine. Feb, 2010 | Pubmed ID: 19851092 Reduced Matrix Metalloproteinase-9 Activity and Cell Death After Global Ischemia in the Brain Preconditioned with Hyperbaric Oxygen Acta Neurochirurgica. Supplement. 2010 | Pubmed ID: 19812919 Caspase-1 Inhibitor Prevents Neurogenic Pulmonary Edema After Subarachnoid Hemorrhage in Mice Stroke; a Journal of Cerebral Circulation. Dec, 2009 | Pubmed ID: 19875734 Matrix Metalloproteinases Inhibition Provides Neuroprotection Against Hypoxia-ischemia in the Developing Brain Journal of Neurochemistry. Nov, 2009 | Pubmed ID: 19712057 Thrombin Inhibition by Argatroban Ameliorates Early Brain Injury and Improves Neurological Outcomes After Experimental Subarachnoid Hemorrhage in Rats Stroke; a Journal of Cerebral Circulation. Apr, 2009 | Pubmed ID: 19228846 Prodeath or Prosurvival: Two Facets of Hypoxia Inducible Factor-1 in Perinatal Brain Injury Experimental Neurology. Mar, 2009 | Pubmed ID: 19041643 HIF-1 Alpha Inhibition Ameliorates Neonatal Brain Damage After Hypoxic-ischemic Injury Acta Neurochirurgica. Supplement. 2008 | Pubmed ID: 19388354 Simvastatin Attenuation of Cerebral Vasospasm After Subarachnoid Hemorrhage in Rats Via Increased Phosphorylation of Akt and Endothelial Nitric Oxide Synthase Journal of Neuroscience Research. Dec, 2008 | Pubmed ID: 18683242 HIF-1alpha Inhibition Ameliorates Neonatal Brain Injury in a Rat Pup Hypoxic-ischemic Model Neurobiology of Disease. Sep, 2008 | Pubmed ID: 18602008 Melatonin Decreases Mortality Following Severe Subarachnoid Hemorrhage Journal of Pineal Research. Mar, 2008 | Pubmed ID: 18289172 Oxidative Stress After Subarachnoid Hemorrhage in Gp91phox Knockout Mice The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Aug, 2007 | Pubmed ID: 17803037 Generation of Integration-free Induced Pluripotent Stem Cells from Human Peripheral Blood Mononuclear Cells Using Episomal Vectors Wei Wen1, Jian-Ping Zhang1, Wanqiu Chen2, Cameron Arakaki2, Xiaolan Li1,2, David Baylink2, Gary D. Botimer3, Jing Xu1, Weiping Yuan1, Tao Cheng1,4,5,6,7, Xiao-Bing Zhang1,2 1State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 2Division of Regenerative Medicine, Department of Medicine, Loma Linda University, 3Department of Orthopaedic Surgery, Loma Linda University, 4Center for Stem Cell Medicine, Chinese Academy of Medical Sciences, 5Department of Stem Cell & Regenerative Medicine, Peking Union Medical College, 6Collaborative Innovation Center for Cancer Medicine, 7Tianjin Key Laboratory of Blood Cell Therapy and Technology JoVE 55091 Entwicklungsbiologie
Generation of Integration-free Induced Pluripotent Stem Cells from Human Peripheral Blood Mononuclear Cells Using Episomal Vectors Wei Wen1, Jian-Ping Zhang1, Wanqiu Chen2, Cameron Arakaki2, Xiaolan Li1,2, David Baylink2, Gary D. Botimer3, Jing Xu1, Weiping Yuan1, Tao Cheng1,4,5,6,7, Xiao-Bing Zhang1,2 1State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 2Division of Regenerative Medicine, Department of Medicine, Loma Linda University, 3Department of Orthopaedic Surgery, Loma Linda University, 4Center for Stem Cell Medicine, Chinese Academy of Medical Sciences, 5Department of Stem Cell & Regenerative Medicine, Peking Union Medical College, 6Collaborative Innovation Center for Cancer Medicine, 7Tianjin Key Laboratory of Blood Cell Therapy and Technology JoVE 55091 Entwicklungsbiologie