Sergii Afonin

Publications

• Structural Dissection of Epsin-1 N-Terminal Helical Peptide: The Role of Hydrophobic Residues in Modulating Membrane Curvature
  Chemistry (Weinheim an Der Bergstrasse, Germany). May, 2023  |   Pubmed ID: 36878866
• Length Matters: Functional Flip of the Short TatA Transmembrane Helix
  Biophysical Journal. Jun, 2023  |   Pubmed ID: 36523158
• Highly Fluorinated Peptide Probes with Enhanced In Vivo Stability for F-MRI
  Small (Weinheim an Der Bergstrasse, Germany). Oct, 2022  |   Pubmed ID: 36074982
• Towards in Vivo Photomediated Delivery of Anticancer Peptides: Insights from Pharmacokinetic and -dynamic Data
  Journal of Photochemistry and Photobiology. B, Biology. Aug, 2022  |   Pubmed ID: 35660309
• Probing and Manipulating the Lateral Pressure Profile in Lipid Bilayers Using Membrane-Active Peptides-A Solid-State F NMR Study
  International Journal of Molecular Sciences. Apr, 2022  |   Pubmed ID: 35562938
• Diarylethene-Based Photoswitchable Inhibitors of Serine Proteases
  Angewandte Chemie (International Ed. in English). Sep, 2021  |   Pubmed ID: 34268844
• Behavior of the Antibacterial Peptide Cyclo[RRRWFW], Explored Using a 3-Hydroxychromone-Derived Fluorescent Amino Acid
  Frontiers in Chemistry. 2021  |   Pubmed ID: 34262894
• TAT-RasGAP Kills Cells by Targeting Inner-leaflet-enriched Phospholipids
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2020  |   Pubmed ID: 33257567
• Structural and Functional Characterization of the Pore-forming Domain of Pinholin S68
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2020  |   Pubmed ID: 33154156
• Diarylethene Moiety As an Enthalpy-entropy Switch: Photoisomerizable Stapled Peptides for Modulating P53/MDM2 Interaction
  Organic & Biomolecular Chemistry. Jul, 2020  |   Pubmed ID: 32390036
• Enhancing the Activity of Membrane Remodeling Epsin-peptide by Trimerization
  Bioorganic & Medicinal Chemistry Letters. Jun, 2020  |   Pubmed ID: 32317210
• Nanomolar Synthesis in Droplet Microarrays with UV-Triggered On-Chip Cell Screening
  Small (Weinheim an Der Bergstrasse, Germany). Mar, 2020  |   Pubmed ID: 31985878
• Light-controllable Dithienylethene-modified Cyclic Peptides: Photoswitching the in Vivo Toxicity in Zebrafish Embryos
  Beilstein Journal of Organic Chemistry. 2020  |   Pubmed ID: 31976015
• Supreme Activity of Gramicidin S Against Resistant, Persistent and Biofilm Cells of Staphylococci and Enterococci
  Scientific Reports. Nov, 2019  |   Pubmed ID: 31784584
• Inhibition of Pseudomonas Aeruginosa Biofilm Formation and Expression of Virulence Genes by Selective Epimerization in the Peptide Esculentin-1a(1-21)NH
  The FEBS Journal. Oct, 2019  |   Pubmed ID: 31144441
• Structure-Activity Relationships of Photoswitchable Diarylethene-Based β-Hairpin Peptides As Membranolytic Antimicrobial and Anticancer Agents
  Journal of Medicinal Chemistry. Dec, 2018  |   Pubmed ID: 30452249
• Efficiently Photocontrollable or Not? Biological Activity of Photoisomerizable Diarylethenes
  Chemistry (Weinheim an Der Bergstrasse, Germany). Aug, 2018  |   Pubmed ID: 29633378
• Orthogonal F-Labeling for Solid-State NMR Spectroscopy Reveals the Conformation and Orientation of Short Peptaibols in Membranes
  Chemistry (Weinheim an Der Bergstrasse, Germany). Mar, 2018  |   Pubmed ID: 29323432
• Flexibility Vs Rigidity of Amphipathic Peptide Conjugates when Interacting with Lipid Bilayers
  Biochimica Et Biophysica Acta. Biomembranes. Dec, 2017  |   Pubmed ID: 28958778
• Lactam-Stapled Cell-Penetrating Peptides: Cell Uptake and Membrane Binding Properties
  Journal of Medicinal Chemistry. Oct, 2017  |   Pubmed ID: 28921993
• Structural Behavior of the Peptaibol Harzianin HK VI in a DMPC Bilayer: Insights from MD Simulations
  Biophysical Journal. Jun, 2017  |   Pubmed ID: 28636916
• Conformational Plasticity of the Cell-Penetrating Peptide SAP As Revealed by Solid-State F-NMR and Circular Dichroism Spectroscopies
  The Journal of Physical Chemistry. B. Jul, 2017  |   Pubmed ID: 28608690
• Loosening of Lipid Packing Promotes Oligoarginine Entry into Cells
  Angewandte Chemie (International Ed. in English). Jun, 2017  |   Pubmed ID: 28597524
• Diphytanoyl Lipids As Model Systems for Studying Membrane-active Peptides
  Biochimica Et Biophysica Acta. Biomembranes. Oct, 2017  |   Pubmed ID: 28587828
• Antimicrobial Peptide Gramicidin S is Accumulated in Granules of Producer Cells for Storage of Bacterial Phosphagens
  Scientific Reports. Mar, 2017  |   Pubmed ID: 28295017
• Orientation and Location of the Cyclotide Kalata B1 in Lipid Bilayers Revealed by Solid-State NMR
  Biophysical Journal. Feb, 2017  |   Pubmed ID: 28256223
• Coding and Decoding Libraries of Sequence-defined Functional Copolymers Synthesized Via Photoligation
  Nature Communications. Nov, 2016  |   Pubmed ID: 27901024
• Delivering Structural Information on the Polar Face of Membrane-Active Peptides: F-NMR Labels with a Cationic Side Chain
  Angewandte Chemie (International Ed. in English). Nov, 2016  |   Pubmed ID: 27761988
• Design, Synthesis, and Application of an Optimized Monofluorinated Aliphatic Label for Peptide Studies by Solid-State F NMR Spectroscopy
  Angewandte Chemie (International Ed. in English). Nov, 2016  |   Pubmed ID: 27706889
• Therapeutic Potential of Gramicidin S in the Treatment of Root Canal Infections
  Pharmaceuticals (Basel, Switzerland). Sep, 2016  |   Pubmed ID: 27618065
• Membrane Thinning and Thickening Induced by Membrane-Active Amphipathic Peptides
  Frontiers in Cell and Developmental Biology. 2016  |   Pubmed ID: 27595096
• Does a Methionine-to-norleucine Substitution in PGLa Influence Peptide-membrane Interactions?
  Biochimica Et Biophysica Acta. Sep, 2016  |   Pubmed ID: 27267703
• Direct Photocontrol of Peptidomimetics: An Alternative to Oxygen-Dependent Photodynamic Cancer Therapy
  Angewandte Chemie (International Ed. in English). Apr, 2016  |   Pubmed ID: 27028784
• Fermentation and Cost-Effective 13C/15N Labeling of the Nonribosomal Peptide Gramicidin S for Nuclear Magnetic Resonance Structure Analysis
  Applied and Environmental Microbiology. Jun, 2015  |   Pubmed ID: 25795666
• γ-(S)-Trifluoromethyl Proline: Evaluation As a Structural Substitute of Proline for Solid State (19)F-NMR Peptide Studies
  Organic & Biomolecular Chemistry. Mar, 2015  |   Pubmed ID: 25703116
• Action of the Multifunctional Peptide BP100 on Native Biomembranes Examined by Solid-state NMR
  Journal of Biomolecular NMR. Apr, 2015  |   Pubmed ID: 25616492
• Control and Role of PH in Peptide-lipid Interactions in Oriented Membrane Samples
  Biochimica Et Biophysica Acta. Mar, 2015  |   Pubmed ID: 25511586
• Structure Analysis and Conformational Transitions of the Cell Penetrating Peptide Transportan 10 in the Membrane-bound State
  PloS One. 2014  |   Pubmed ID: 24937132
• (19)F NMR Screening of Unrelated Antimicrobial Peptides Shows That Membrane Interactions Are Largely Governed by Lipids
  Biochimica Et Biophysica Acta. Sep, 2014  |   Pubmed ID: 24699372
• Controlling Biological Activity with Light: Diarylethene-containing Cyclic Peptidomimetics
  Angewandte Chemie (International Ed. in English). Mar, 2014  |   Pubmed ID: 24554486
• Stereochemical Effects on the Aggregation and Biological Properties of the Fibril-forming Peptide [KIGAKI]3 in Membranes
  Physical Chemistry Chemical Physics : PCCP. Jun, 2013  |   Pubmed ID: 23652359
• Incorporation of Cis- and Trans-4,5-difluoromethanoprolines into Polypeptides
  Organic Letters. Oct, 2012  |   Pubmed ID: 23020292
• Structure Analysis of the Membrane-bound PhoD Signal Peptide of the Tat Translocase Shows an N-terminal Amphiphilic Helix
  Biochimica Et Biophysica Acta. Dec, 2012  |   Pubmed ID: 22960285
• Antimicrobial Peptides Can Enhance the Risk of Persistent Infections
  Frontiers in Immunology. 2012  |   Pubmed ID: 22870073
• Hydrophobic Matching Controls the Tilt and Stability of the Dimeric Platelet-derived Growth Factor Receptor (PDGFR) β Transmembrane Segment
  The Journal of Biological Chemistry. Jul, 2012  |   Pubmed ID: 22619173
• Alignment of Druglike Compounds in Lipid Bilayers Analyzed by Solid-state (19)F-NMR and Molecular Dynamics, Based on Dipolar Couplings of Adjacent CF3 Groups
  The Journal of Physical Chemistry. B. Apr, 2012  |   Pubmed ID: 22439912
• Solid-state (19)F-NMR of Peptides in Native Membranes
  Topics in Current Chemistry. 2012  |   Pubmed ID: 21598096
• Special Issue on Membrane-active Peptides
  European Biophysics Journal : EBJ. Apr, 2011  |   Pubmed ID: 21286705
• Structural Role of the Conserved Cysteines in the Dimerization of the Viral Transmembrane Oncoprotein E5
  Biophysical Journal. Sep, 2010  |   Pubmed ID: 20858420
• 19F NMR Analysis of the Antimicrobial Peptide PGLa Bound to Native Cell Membranes from Bacterial Protoplasts and Human Erythrocytes
  Journal of the American Chemical Society. Jul, 2010  |   Pubmed ID: 20550126
• Dynamic Transitions of Membrane-active Peptides
  Methods in Molecular Biology (Clifton, N.J.). 2010  |   Pubmed ID: 20094866
• Chemical Labeling Strategy with (R)- and (S)-trifluoromethylalanine for Solid State 19F NMR Analysis of Peptaibols in Membranes
  Journal of the American Chemical Society. Nov, 2009  |   Pubmed ID: 19827760
• Solid State NMR Structure Analysis of the Antimicrobial Peptide Gramicidin S in Lipid Membranes: Concentration-Dependent Re-alignment and Self-Assembly As A β-Barrel
  Topics in Current Chemistry. 2008  |   Pubmed ID: 23605461
• Using a Sterically Restrictive Amino Acid As a 19F NMR Label to Monitor and to Control Peptide Aggregation in Membranes
  Journal of the American Chemical Society. Dec, 2008  |   Pubmed ID: 19554688
• Temperature-dependent Transmembrane Insertion of the Amphiphilic Peptide PGLa in Lipid Bilayers Observed by Solid State 19F NMR Spectroscopy
  Journal of the American Chemical Society. Dec, 2008  |   Pubmed ID: 19049452
• Conformation and Membrane Orientation of Amphiphilic Helical Peptides by Oriented Circular Dichroism
  Biophysical Journal. Oct, 2008  |   Pubmed ID: 18621832
• Synthesis of Trifluoromethyl-substituted Proline Analogues As 19F NMR Labels for Peptides in the Polyproline II Conformation
  Angewandte Chemie (International Ed. in English). 2008  |   Pubmed ID: 18576439