Journal
/
神经科学
/
A Neonatal Rodent Model of Retroorbital Vein Injection
JoVE 杂志
神经科学
Author Produced
This content is Free Access.
JoVE 杂志 神经科学
A Neonatal Rodent Model of Retroorbital Vein Injection

A Neonatal Rodent Model of Retroorbital Vein Injection

DOI:
10.3791/65386-v

•

04:39 min

•

February 23, 2024

•

, , , , , ,
1Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Department of Obstetrics and Gynecology, Sahlgrenska Academy,University of Gothenburg, 2Centre of Perinatal Medicine and Health, Institute of Neuroscience and Physiology, Sahlgrenska Academy,University of Gothenburg

Chapters

  • 00:11Introduction
  • 01:47Needle and Solution
  • 02:01Setup
  • 02:23Injection Procedure
  • 03:15Representative Results
  • 04:01Conclusion

Summary

自动翻译

自动翻译

This protocol aims to demonstrate a reproducible venous administration route that can be used in rats and mice throughout the neonatal period. This procedure is important for preclinical rodent studies that wish to mirror drug administration in neonatal care units primarily using intravenous administration.

Tags

Retroorbital Vein InjectionNeonatal Rodent ModelIntravenous InjectionAnimal ResearchTail Vein InjectionVenous CirculationOrbital Venous AnatomyTrypan BlueIsoflurane AnesthesiaPull Withdrawal Reflex

Article

Embed

添加到播放列表

Usage Statistics

Related Videos

Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice

Neonatal Subventricular Zone Electroporation

A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation

Intracerebroventricular Viral Injection of the Neonatal Mouse Brain for Persistent and Widespread Neuronal Transduction

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Neurobehavioral Assessments in a Mouse Model of Neonatal Hypoxic-ischemic Brain Injury

Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult

Preparation of Rhythmically-active In Vitro Neonatal Rodent Brainstem-spinal Cord and Thin Slice

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model

Read Article