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Dosage-Adjusted Resistance Training in Mice with a Reduced Risk of Muscle Damage
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神经科学
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JoVE 杂志 神经科学
Dosage-Adjusted Resistance Training in Mice with a Reduced Risk of Muscle Damage

Dosage-Adjusted Resistance Training in Mice with a Reduced Risk of Muscle Damage

DOI:
10.3791/64000-v

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07:29 min

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August 31, 2022

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, , , , , , , , ,
1Physical Therapy Program, Department of Health Care Sciences, Eugene Applebaum College of Pharmacy and Health Sciences,Wayne State University, 2Department of Pharmacology,University of Nevada, Reno School of Medicine

Chapters

  • 00:05Introduction
  • 01:27Preparation of Mice for DART or ISOM
  • 03:37DART or ISOM Training
  • 06:10Results: Histological Study after DART and ISOM Training
  • 06:35Conclusion

Summary

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The present protocol describes a unique technique called dosage-adjusted resistance training (DART), which can be incorporated into precision rehabilitation studies performed in small animals, such as mice.

Tags

Dosage-adjusted Resistance TrainingMuscle DamageMiceAnterior Tibial MusclesEccentrically Biased ContractionsSciatic NerveElectrical StimulationIsothermal Gel Heating PadDepilatory CreamLidocaine CreamTibial Stabilizing PinDART DeviceFootplate

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