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The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
JoVE 杂志
行为学
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JoVE 杂志 行为学
The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

2,487 Views

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05:40 min

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April 28, 2022

DOI:

10.3791/63576-v

DOI:
10.3791/63576-v

•

05:40 min
April 28, 2022

•

6 Views
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1Human Psychopharmacology Laboratory, Division of Intramural Clinical and Biological Research,NIAAA, 2Dept. of Psychiatry,Indiana University School of Medicine, 3R.L. Roudebush VA Medical Center

Summary

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This study aims to show that the Progressive-Ratio Computer-assisted Alcohol-Infusion System (CAIS) paradigm is a reliable and sensitive method that can be used to examine the motivating properties associated with alcohol self-administration in humans.

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Progressive-ratioAlcohol Self-administrationAlcohol RewardAlcohol Use DisorderRisky DrinkingMedicationIntravenousHuman ParticipantsComputer ControlSoftwareExperiment Setup

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Cite this Article

Stangl, B. L., Byrd, N. D., Soundararajan, S., Plawecki, M. H., O’Connor, S., Ramchandani, V. A. The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans. J. Vis. Exp. (182), e63576, doi:10.3791/63576 (2022).

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