This work describes the development of flexible interdigitated electrodes for implementation in 3D brain tumor models, namely, in vitro culture, in ovo model, and in vivo murine model. The proposed method can be used to evaluate the effects of pulsed electric fields on tumors at different levels of complexity.
Lefevre, M. C., Kaszas, A., Dijk, G., Baca, M., Baudino, O., Marchiori, B., Kergoat, L., Moreau, D., Debarbieux, F., O'Connor, R. P. Flexible Organic Electronic Devices for Pulsed Electric Field Therapy of Glioblastoma. J. Vis. Exp. (186), e63527, doi:10.3791/63527 (2022).