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对成年 冈比亚按蚊 的有效口服RNA干扰（RNAi）给药
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March 01, 2022
DOI:
1Division of Parasitic Diseases and Malaria, Entomology Branch,Centers for Disease Control and Prevention, 2Department of Entomology,Cornell University, 3Centro de Estudios en Biotecnologia,Universidad del Valle de Guatemala, 4Department of Cell Biology,Johns Hopkins School of Medicine, 5Johns Hopkins Malaria Research Institute,Johns Hopkins Bloomberg School of Public Health, 6Department of Molecular Microbiology and Immunology,Johns Hopkins Bloomberg School of Public Health and Malaria Research Institute, 7Department of Cell Biology,Johns Hopkins School of Medicine, 8Biomedical Sciences Department,Idaho College of Osteopathic Medicine
Summary
Automatically generated
口服由细菌产生的dsRNA，一种常规用于 秀丽隐杆线虫 的RNA干扰（RNAi）递送方法，在这里成功地应用于成年蚊子。我们的方法允许在不使用注射的情况下进行稳健的反向遗传学研究和传播阻断载体研究。
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Cite this Article
Taracena, M., Hunt, C., Pennington, P., Andrew, D., Jacobs-Lorena, M., Dotson, E., Wells, M. Effective Oral RNA Interference (RNAi) Administration to Adult Anopheles gambiae Mosquitoes. J. Vis. Exp. (181), e63266, doi:10.3791/63266 (2022).
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