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Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
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07:23 min
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August 06, 2021
DOI:
1Department of Pathology & Cell Biology; Vagelos College of Physicians and Surgeons,Columbia University, 2Department of Molecular Pharmacology and Therapeutics; Vagelos College of Physicians and Surgeons,Columbia University, 3Department of Neurology; Vagelos College of Physicians and Surgeons,Columbia University, 4The Taub Institute for Research on Alzheimer’s Disease and the Aging Brain; Vagelos College of Physicians and Surgeons,Columbia University
Summary
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Here, we describe an optimized protocol for retinal vein occlusion using rose bengal and a laser-guided retinal imaging microscope system with recommendations to maximize its reproducibility in genetically modified strains.
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Colón Ortiz, C., Potenski, A., Lawson, J. M., Smart, J., Troy, C. M. Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability. J. Vis. Exp. (174), e62980, doi:10.3791/62980 (2021).
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