Journal
/
医学
/
A Preclinical Model of Exertional Heat Stroke in Mice
JoVE 杂志
医学
需要订阅 JoVE 才能查看此.  登录或开始免费试用。
JoVE 杂志 医学
A Preclinical Model of Exertional Heat Stroke in Mice

A Preclinical Model of Exertional Heat Stroke in Mice

DOI:
10.3791/62738-v

•

08:22 min

•

July 01, 2021

•

, , ,
1Department of Applied Physiology and Kinesiology, College of Health and Human Performance,University of Florida, 2Department of Nutrition and Integrative Physiology, College of Health and Human Sciences,Florida State University

Chapters

  • 00:05Introduction
  • 00:55Surgical Implantation of the Telemetric Temperature Monitoring System
  • 02:35EHS Protocol
  • 06:43Results: Exertional Heat Stroke in Mice
  • 07:42Conclusion

Summary

自动翻译

自动翻译

The protocol describes the development of a standardized, repeatable, preclinical model of exertional heat stroke (EHS) in mice free from adverse external stimuli such as electric shock. The model provides a platform for mechanistic, preventative, and therapeutic studies.

Tags

Keywords: Preclinical ModelExertional Heat StrokeMiceTelemetrySurgical ImplantationCore Temperature MonitoringEnvironmental ChamberAnesthesiaBuprenorphineAseptic TechniqueRecovery

Article

Embed

添加到播放列表

Usage Statistics

Related Videos

check_url/cn/62738?article_type=v

Modeling Stroke in Mice – Middle Cerebral Artery Occlusion with the Filament Model
check_url/cn/62738?article_type=v

Gene Transfer for Ischemic Heart Failure in a Preclinical Model
check_url/cn/62738?article_type=v

Intraluminal Middle Cerebral Artery Occlusion (MCAO) Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Mice
check_url/cn/62738?article_type=v

A Murine Model of Subarachnoid Hemorrhage
check_url/cn/62738?article_type=v

Excitotoxic Stimulation of Brain Microslices as an In vitro Model of Stroke
check_url/cn/62738?article_type=v

A Preclinical Murine Model of Hepatic Metastases
check_url/cn/62738?article_type=v

Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery
check_url/cn/62738?article_type=v

A Simple Critical-sized Femoral Defect Model in Mice
check_url/cn/62738?article_type=v

Surgical Approach for Middle Cerebral Artery Occlusion and Reperfusion Induced Stroke in Mice
check_url/cn/62738?article_type=v

PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke

Read Article