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通过心血管磁共振成像定量小鼠心脏左心室功能、心肌劳损和血流动力学力
JoVE 杂志
生物工程
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JoVE 杂志 生物工程
Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging
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通过心血管磁共振成像定量小鼠心脏左心室功能、心肌劳损和血流动力学力

DOI:
10.3791/62595-v

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11:13 min

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May 24, 2021

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, , , , , ,
1Department of Biomedical Engineering & Physics, Amsterdam University Medical Centers, Amsterdam Cardiovascular Sciences,University of Amsterdam, 2BioMedical Engineering and Imaging Institute,Icahn School of Medicine at Mount Sinai, 3MR Solutions Ltd., 4Laboratory for Myology, Department of Human Movement Sciences, Faculty of Behavioral and Movement Sciences,Vrije Universiteit Amsterdam, 5Medis medical imaging systems B.V.

Chapters

  • 00:05Introduction
  • 00:51Setup and Animal Preparation
  • 01:49MRI Scan Calibration and Triggering, Planning and Acquisition
  • 06:05Offline Reconstruction of the Retrospectively Acquired Scans
  • 07:15Image Analysis Software
  • 09:21Results: Quantification of Mouse Heart Left Ventricular Parameters by Cardiovascular Magnetic Resonance Imaging
  • 10:27Conclusion

Summary

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自动翻译

本研究描述了一种全面的心血管磁共振成像（CMR）方案，以量化小鼠心脏的左心室功能参数。该协议描述了CMR图像的采集，后处理和分析以及不同心脏功能参数的评估。

Tags

Cardiovascular Magnetic Resonance ImagingMouse HeartLeft Ventricular FunctionMyocardial StrainHemodynamic ForcesEjection FractionE/A RatioGlobal Longitudinal StrainHeart FailureECG GatingRespiratory GatingGradient Echo Scout ScanShort-axis ViewLong-axis View

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