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Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery
JoVE 杂志
生物化学
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JoVE 杂志 生物化学
Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery

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06:26 min

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May 16, 2021

DOI:

10.3791/62469-v

DOI:
10.3791/62469-v

•

06:26 min
May 16, 2021

•

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1Oncode Institute and Division of Biochemistry,the Netherlands Cancer Institute, 2Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ),Johann Wolfgang Goethe-University

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Ahmad, M. U. D., Fish, A., Molenaar, J., Sreeramulu, S., Richter, C., Altincekic, N., Schwalbe, H., Wienk, H., Perrakis, A. Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery. J. Vis. Exp. (171), e62469, doi:10.3791/62469 (2021).

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