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Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson’s Disease
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神经科学
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JoVE 杂志 神经科学
Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson’s Disease

Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson’s Disease

DOI:
10.3791/62002-v

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04:08 min

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January 18, 2021

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, , , , , ,
1Department of Neurological Sciences,University of Nebraska Medical Center

Chapters

  • 00:05Introduction
  • 00:35Gait Procedure
  • 01:45Results: Gait Analysis Outcomes
  • 03:20Conclusion

Summary

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Here we describe the RatWalker system, built by redesigning the MouseWalker apparatus to accommodate for the increased size and weight of rats. This system uses frustrated total internal reflection (FTIR), high-speed video capture, and open-access analysis software to track and quantify gait parameters.

Tags

Gait AnalysisParkinson’s DiseaseGenetic Rat ModelRatWalker SystemKinematic Gait ParametersStance PhaseSwing DurationDuty FactorWalking SpeedStep Length

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