需要订阅 JoVE 才能查看此. 登录或开始免费试用。
Differentiation of Monocytes into Phenotypically Distinct Macrophages After Treatment with Human Cord Blood Stem Cell (CB-SC)-Derived Exosomes
5,554 Views
•
09:20 min
•
November 12, 2020
DOI:
Summary
Automatically generated
Exosome application is an emerging tool for drug development and regenerative medicine. We establish an exosome isolation protocol with high purity to isolate exosomes from novel identified stem cells called CB-SC for mechanistic studies. We also coculture CB-SC-derived exosomes with human monocytes, leading to their differentiation into phenotypically distinct macrophages.
Read Article
Cite this Article
Hu, W., Song, X., Yu, H., Sun, J., Zhao, Y. Differentiation of Monocytes into Phenotypically Distinct Macrophages After Treatment with Human Cord Blood Stem Cell (CB-SC)-Derived Exosomes. J. Vis. Exp. (165), e61562, doi:10.3791/61562 (2020).
Copy