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从小鼠佩耶的补丁中对Germinal中心B细胞JH4因特龙的体细胞突变分析

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免疫与感染

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JoVE 杂志免疫与感染

Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer’s Patches

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从小鼠佩耶的补丁中对Germinal中心B细胞JH4因特龙的体细胞突变分析

6,279 Views

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09:35 min

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April 20, 2021

DOI:

10.3791/61551-v

DOI:

10.3791/61551-v

•

09:35 min

April 20, 2021

•

1 Views

Emily Sible, Simin Zheng, Jee Eun Choi, Bao Q. Vuong

¹Department of Biology,The City College of New York and The Graduate Center of The City University of New York, ²Department of Microbiology,Icahn School of Medicine at Mount Sinai

Tags

Somatic Hypermutation JH4 Intron Germinal Center B Cells Peyer’s Patches Antibody Diversification Molecular Biology PCR Sanger Sequencing Cell Isolation

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