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Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens
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Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens

3,266 Views

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13:47 min

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May 19, 2020

DOI:

10.3791/60873-v

DOI:
10.3791/60873-v

•

13:47 min
May 19, 2020

•

3 Views
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1Bacteriology Division,United States Army Medical Research Institute of Infectious Diseases, 2Headquarters Division,United States Army Medical Research Institute of Infectious Diseases, 3Bioqual

Summary

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The opsono-adherence assay is an alternative method to the opsono-phagocytic killing assay to evaluate the opsonic functions of antibodies in vaccine development.

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Chua, J., Chabot, D. J., Putmon-Taylor, T., Friedlander, A. M. Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens. J. Vis. Exp. (159), e60873, doi:10.3791/60873 (2020).

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