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Cell Surface Receptor Identification Using Genome-Scale CRISPR/Cas9 Genetic Screens
JoVE 杂志
遗传学
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JoVE 杂志 遗传学
Cell Surface Receptor Identification Using Genome-Scale CRISPR/Cas9 Genetic Screens

Cell Surface Receptor Identification Using Genome-Scale CRISPR/Cas9 Genetic Screens

13,634 Views

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08:49 min

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June 06, 2020

DOI:

10.3791/60803-v

DOI:
10.3791/60803-v

•

08:49 min
June 06, 2020

•

26 Views
,
1Cell Surface Signalling Laboratory,Wellcome Trust Sanger Institute, 2EMBL-EBI,Wellcome Genome Campus

Summary

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This manuscript describes a genome-scale cell-based screening approach to identify extracellular receptor-ligand interactions.

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Cite this Article

Sharma, S., Wright, G. J. Cell Surface Receptor Identification Using Genome-Scale CRISPR/Cas9 Genetic Screens. J. Vis. Exp. (160), e60803, doi:10.3791/60803 (2020).

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