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Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model
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JoVE 杂志 免疫与感染
Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model

Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model

DOI:
10.3791/60515-v

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09:32 min

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February 23, 2020

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, , ,
1Division of Cardiovascular Medicine,University of Missouri, 2Medical Pharmacology and Physiology,University of Missouri, 3Dalton Cardiovascular Research Center,University of Missouri

Chapters

  • 00:04Introduction
  • 01:11Mouse Preparation
  • 02:07Abdominal Aorta Imaging
  • 04:47Abdominal Aortic Image Analysis
  • 05:13Pulse Propagation Velocity (PPV) Analysis
  • 05:48Distensibility and Radial Strain Analysis
  • 06:47Results: Representative PPV and Aortic Structural Analyses in an Established Abdominal Aortic Aneurysm (AAA) Model
  • 08:31Conclusion

Summary

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This manuscript describes a detailed protocol for using high frequency ultrasound imaging to measure luminal diameter, pulse propagation velocity, distensibility and radial strain on a mouse model of abdominal aortic aneurysm.

Tags

Keywords: Aortic AneurysmUltrasound ImagingPulse Wave VelocityAortic DistensibilityAortic StrainCardiovascular DiseasePreclinical TrialsNon-invasive Technique

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