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Stamcelle afledte virale AG-specifikke T-lymfocytter undertrykker HBV-replikation i mus
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免疫与感染
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JoVE 杂志 免疫与感染
Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
DOI:

07:25 min

September 25, 2019

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Chapters

  • 00:04Title
  • 00:34Antigen (Ag)‐ Specific CD8+ T cell Generation
  • 02:01Hydrodynamic Herpes B Virus (HBV) Plasmid Delivery for HBV Replication Induction
  • 02:43HBV Replication Reduction
  • 03:38HBV Replication Reduction Analysis
  • 05:30Results: Representative Effects of Stem Cell-Derived Viral Ag-Specific T Lymphocyte HBV Replication Suppression
  • 06:58Conclusion

Summary

自动翻译

Præsenteret her er en protokol til effektiv undertrykkelse af hepatitis B virus (HBV) replikation i mus ved at udnytte adoptiv celle overførsel (ACT) af stamcelle-afledte viral antigen (AG)-specifikke T-lymfocytter. Denne procedure kan tilpasses til potentiel ACT-baseret immunterapi af HBV-infektion.

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