This content is Free Access.
Geração de fibrilas pré-formadas Alpha-synuclein de monômeros e uso in vivo
20,402 Views
•
09:44 min
•
June 02, 2019
DOI:
1Department of Translational Science and Molecular Medicine,Michigan State University, 2The Michael J. Fox Foundation for Parkinson’s Research, 3Neuroscience Program,Michigan State University, 4Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine,University of Pennsylvania Perelman School of Medicine, 5Center for Neurodegeneration and Experimental Therapeutics,University of Alabama at Birmingham, 6Mercy Health Hauenstein Neuroscience Medical Center
Summary
Automatically generated
O objetivo deste artigo é delinear as etapas necessárias para a geração de fibrilas de alfa-synucleina monomérica, controle de qualidade subsequente e uso das fibrilas pré-formadas in vivo.
Read Article
Cite this Article
Patterson, J. R., Polinski, N. K., Duffy, M. F., Kemp, C. J., Luk, K. C., Volpicelli-Daley, L. A., Kanaan, N. M., Sortwell, C. E. Generation of Alpha-Synuclein Preformed Fibrils from Monomers and Use In Vivo. J. Vis. Exp. (148), e59758, doi:10.3791/59758 (2019).
Copy