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Inducement and Evaluation of a Murine Model of Experimental Myopia
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神经科学
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JoVE 杂志 神经科学
Inducement and Evaluation of a Murine Model of Experimental Myopia

Inducement and Evaluation of a Murine Model of Experimental Myopia

DOI:
10.3791/58822-v

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07:20 min

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January 22, 2019

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, , , , , ,
1Laboratory of Photobiology,Keio University School of Medicine, 2Department of Ophthalmology,Keio University School of Medicine

Chapters

  • 00:04Title
  • 00:46Mouse Eyeglasses Assembly and Refraction and Axial Length (AL) Baseline Measurements
  • 03:14Mouse Cranium Frame Fixation and Myopia Induction and Maintenance
  • 05:16Results: Representative Myopia Inducement in Mice
  • 06:39Conclusion

Summary

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In this protocol, we describe the full process of experimental myopia inducement in mice using newly designed eyeglasses and the technic needed for achieving stable and reproducible results in ocular parameter measurements.

Tags

Keywords: Murine ModelExperimental MyopiaLens-induced MyopiaMouseEyeglasses FrameCyanoacrylate AdhesiveMydriatic AgentRefractionAxial LengthOptical Coherence Tomography

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