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小鼠骨髓基质树突状细胞诱导 CD4 T 细胞活化、增殖和 Th1 分化的体外模型研究
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An In Vivo Mouse Model to Measure Naïve CD4 T Cell Activation, Proliferation and Th1 Differentiation Induced by Bone Marrow-derived Dendritic Cells
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小鼠骨髓基质树突状细胞诱导 CD4 T 细胞活化、增殖和 Th1 分化的体外模型研究

18,955 Views

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08:39 min

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August 22, 2018

DOI:

10.3791/58118-v

DOI:
10.3791/58118-v

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08:39 min
August 22, 2018

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6 Views
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1LamImSys Lab,Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 2LamImSys Lab,Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), 3CIBER de Enfermedades Cardiovasculares

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In VivoMouse ModelNaive CD4 T CellActivationProliferationTh1 DifferentiationBone Marrow-derived Dendritic CellsT-cell ActivationAdaptive ImmunityAntigen Presenting CellBone Marrow Cell IsolationLymph Node IsolationSpleen IsolationOT-II Transgenic Mice

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Toribio-Fernandez, R., Zorita, V., Herrero-Fernandez, B., Gonzalez-Granado, J. M. An In Vivo Mouse Model to Measure Naïve CD4 T Cell Activation, Proliferation and Th1 Differentiation Induced by Bone Marrow-derived Dendritic Cells. J. Vis. Exp. (138), e58118, doi:10.3791/58118 (2018).

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