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感染 Ifnar1 小鼠 Immunoprivileged 器官寨卡病毒特异 T 细胞反应的评价
JoVE 杂志
免疫与感染
This content is Free Access.
JoVE 杂志 免疫与感染
Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1-/- Mice
DOI:

10:01 min

October 17, 2018

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Chapters

  • 00:04Title
  • 01:15Zika Virus (ZIKV) Infection, Immunization, and Splenic Monocyte Isolation
  • 03:19Brain and Testicular Monocyte Isolation
  • 06:10Flow Cytometry
  • 07:26Results: ZIKV Infection Characterization in Ifnar1-/- Mice
  • 09:10Conclusion

Summary

自动翻译

本文介绍了一种评估 Ifnar1-小鼠寨卡病毒 (ZIKV) 感染 immunoprivileged 器官抗原特异 T 细胞反应的协议。该方法对 ZIKV 疫苗的保护和免疫发病机制细胞机制的研究具有重要意义, 对其疗效评价也有参考价值。

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