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A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage
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July 28, 2018
DOI:
1Department of Neurosurgery,Medical Center of the Johannes Gutenberg – University, 2Department of Neuroradiology,Medical Center of the Johannes Gutenberg – University, 3Platform for Biomaterial Research,Medical Center of the Johannes Gutenberg – University, 4Department of Anesthesiology,Medical Center of the Johannes Gutenberg – University
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The goal of this article is to present a method that allows a 3-dimensional reconstruction of the cerebrovascular tree in mice after micro computed tomography and determination of volumes of entire vessel segments that can be used to quantify cerebral vasospasm in murine models of subarachnoid hemorrhage.
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Neulen, A., Kosterhon, M., Pantel, T., Kirschner, S., Goetz, H., Brockmann, M. A., Kantelhardt, S. R., Thal, S. C. A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage. J. Vis. Exp. (137), e57997, doi:10.3791/57997 (2018).
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