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In Vivo Electrophysiological Measurement of the Rat Ulnar Nerve with Axonal Excitability Testing
JoVE 杂志
神经科学
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JoVE 杂志 神经科学
In Vivo Electrophysiological Measurement of the Rat Ulnar Nerve with Axonal Excitability Testing

In Vivo Electrophysiological Measurement of the Rat Ulnar Nerve with Axonal Excitability Testing

DOI:
10.3791/56102-v

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04:56 min

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February 06, 2018

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, , , , ,
1School of Medical Science,University of New South Wales, 2Department of Clinical Neurophysiology, Rigshospitalet and the Institute of Neuroscience and Pharmacology,University of Copenhagen, 3Prince of Wales Clinical School,University of New South Wales

Chapters

  • 00:05Title
  • 00:43Axonal Excitability Procedure
  • 03:00Results: Representative Axonal Excitability Measurements
  • 04:07Conclusion

Summary

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Axonal excitability techniques provide a powerful tool to examine pathophysiology and biophysical changes that precede irreversible degenerative events. This manuscript demonstrates the use of these techniques on the ulnar nerve of anesthetized rats.

Tags

Keywords: In VivoElectrophysiologicalRatUlnar NerveAxonal Excitability TestingCompound Muscle Action PotentialStimulating ElectrodeRecording ElectrodeThreshold TrackingStimulus Response CurveAxonal Excitability ParametersThreshold ElectrotonusCurrent Threshold RelationshipRecovery Cycle

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