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A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia
JoVE 杂志
神经科学
Author Produced
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JoVE 杂志 神经科学
A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

DOI:
10.3791/55277-v

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09:59 min

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September 16, 2017

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, , , ,
1School of Experimental Psychology and Clinical Research and Imaging Center Bristol,University of Bristol, 2Department of Neurobiology, A.I. Virtanen Institute,University of Eastern Finland

Chapters

  • 00:00Title
  • 01:14Methods: Animal Model
  • 04:08Methods: MRI
  • 04:49Methods: Lesion Verification
  • 05:06Methods: Image Processing/Data Analysis
  • 07:57Results
  • 08:47Conclusions

Summary

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A protocol for stroke onset time estimation in a rat model of stroke exploiting quantitative magnetic resonance imaging (qMRI) parameters is described. The procedure exploits diffusion MRI for delineation of the acute stroke lesion and quantitative T1 and T2 (qT1 and qT2) relaxation times for timing of stroke.

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Magnetic Resonance ImagingStroke Onset TimeIschemic StrokeApparent Diffusion CoefficientT1 And T2 Relaxation TimesPermanent Focal IschemiaMiddle Cerebral Artery OcclusionRat ModelSemi-automated Computer Routine

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