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שיטת הזרקה אלטרנטיבית והמאומתת עבור גישת שטח subretinal<i> דרך</i> בגישה אחורית Transcleral
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An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach
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שיטת הזרקה אלטרנטיבית והמאומתת עבור גישת שטח subretinal<i> דרך</i> בגישה אחורית Transcleral

12,890 Views

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07:13 min

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December 07, 2016

DOI:

10.3791/54808-v

DOI:
10.3791/54808-v

•

07:13 min
December 07, 2016

•

6 Views
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1Jules Stein Eye Institute,University of California, Los Angeles

Summary

Automatically generated

Subretinal injections are the most common technique for delivering large therapeutic agents such as proteins and viral vectors to photoreceptors and the retinal pigment epithelium. An alternative method in mice that successfully targets the subretinal space with minimal collateral damage and fast recovery times is described here.

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Cite this Article

Parikh, S., Le, A., Davenport, J., Gorin, M. B., Nusinowitz, S., Matynia, A. An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach. J. Vis. Exp. (118), e54808, doi:10.3791/54808 (2016).

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