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İşlevsel Genomik Tarama kullanılması Kanser Hücre Sfero Kültürleri Potansiyel Yeni İlaç Hedefleri Belirlemek İçin
Chapters
- 00:05Title
- 01:17Reverse Transfection of BT474 Cells
- 03:51Automated Image Acquisition
- 05:23Results: Functional Genomic Investigation of BT474 Spheroids Uncovers Oncogenic Dependencies
- 07:02Conclusion
Identifying novel drug targets that transition from pre-clinical testing to human trials is a scientific priority. To that end, here we describe a functional genomics approach for examining the impact of gene depletion on cancer cell line spheroids, which more appropriately model human cancers in vivo.
