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JoVE Journal Behavior
Novel Object Exploration as a Potential Assay for Higher Order Repetitive Behaviors in Mice
 

Novel Object Exploration as a Potential Assay for Higher Order Repetitive Behaviors in Mice

Article DOI: 10.3791/54324-v • 08:28 min • August 20th, 2016
August 20th, 2016 •
1, 1, 1
1Department of Biology, University of Redlands

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Higher order restricted, repetitive behaviors (RRBs) disrupt the lives of affected individuals. These behaviors are challenging to model in rodents, making basic biomedical research into potential treatments or interventions for RRBs difficult. Here we describe novel object exploration as a potential assay for higher order RRBs in mice.

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Novel Object Exploration Higher Order Repetitive Behaviors Mice Behavioral Assay Mouse Models Autistic-like Behavior C58J Mouse Strain Advantages No Training Required Not Anxiety-provoking Testing Arena Plastic Cage Corn Cob Bedding Novel Objects Shape Color Pink Toy Brick Red Monkey White Tile With Blue Writing Standard White Die High Density Plastic Cleaning Resistance Chewing Resistance Placement Recording Camera Positioning Acclimation Period Rest Period Light Cycle Start Fluorescent Lighting Lux Level Standardization Video Recording
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