Journal
/
医学
/
Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
JoVE 杂志
医学
需要订阅 JoVE 才能查看此.  登录或开始免费试用。
JoVE 杂志 医学
Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs

Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs

DOI:
10.3791/53878-v

•

10:02 min

•

July 23, 2016

•

, , , , , , , ,
1Department of Ophthalmology,Seoul National University Bundang Hospital, 2Department of Ophthalmology, College of Medicine,Seoul National University, 3Department of Ophthalmology,Hanyang University Hospital, 4Department of Ophthalmology,Seoul Metropolitan Government-Seoul National University Boramae Medical Center, 5Department of Clinical Pharmacology,Seoul National University Hospital, 6Department of Clinical Pharmacology,Seoul National University Bundang Hospital

Chapters

  • 00:05Title
  • 01:16Intraocular Injection of Drug into Rabbit Eyes
  • 02:42Sample Preparation
  • 06:04Immunoassay and Pharmacokinetic Analysis Methods
  • 07:41Results: Pharmacokinetic Studies of Intraocular Drugs
  • 08:53Conclusion

Summary

自动翻译

自动翻译

Rabbits are widely used to study the pharmacokinetics of intraocular drugs. We describe a method for conducting pharmacokinetic studies of intraocular drugs using rabbit eyes.

Tags

Keywords: PharmacokineticsIntraocular DrugsRabbit EyesIntravitreal InjectionOcular PharmacologyOcular Drug DeliveryDrug ConcentrationDrug DistributionIntraocular InflammationConjunctival IncisionEnucleation

Article

Embed

添加到播放列表

Usage Statistics

Related Videos

check_url/cn/53878?article_type=v

Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice
check_url/cn/53878?article_type=v

The Rabbit Blood-shunt Model for the Study of Acute and Late Sequelae of Subarachnoid Hemorrhage: Technical Aspects
check_url/cn/53878?article_type=v

Assessing Specificity of Anticancer Drugs In Vitro
check_url/cn/53878?article_type=v

A Mouse Model of Retinal Ischemia-Reperfusion Injury Through Elevation of Intraocular Pressure
check_url/cn/53878?article_type=v

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
check_url/cn/53878?article_type=v

Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research
check_url/cn/53878?article_type=v

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
check_url/cn/53878?article_type=v

Transthoracic Echocardiographic Examination in the Rabbit Model
check_url/cn/53878?article_type=v

A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies
check_url/cn/53878?article_type=v

Self-Administration of Drugs in Mouse Models of Feeding and Obesity

Read Article