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The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse
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May 16, 2016
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Osteoarthritis (OA), or degenerative joint disease, is a debilitating condition associated with pain that remains only partially controlled by available analgesics. Animal models are being developed to improve our understanding of OA-related pain mechanisms. Here we describe the methodology for the monoiodoacetate model of OA pain in the mouse.
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Pitcher, T., Sousa-Valente, J., Malcangio, M. The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse. J. Vis. Exp. (111), e53746, doi:10.3791/53746 (2016).
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