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Electrophysiology on Isolated Brainstem-spinal Cord Preparations from Newborn Rodents Allows Neural Respiratory Network Output Recording
 

Electrophysiology on Isolated Brainstem-spinal Cord Preparations from Newborn Rodents Allows Neural Respiratory Network Output Recording

Article DOI: 10.3791/53071-v 05:28 min November 19th, 2015
November 19th, 2015

章节

总结概括

The central respiratory drive is located in the brainstem. Spontaneous respiratory motor output from an isolated brainstem-spinal cord is recorded by placing an electrode on the fourth ventral root. This experimental approach is valuable for pharmacological investigations or the assessment of respiratory challenges and genetic manipulations on rhythmic motor behavior.

Tags

Keywords: Electrophysiology Brainstem-spinal Cord Preparation Newborn Rodents Neural Respiratory Network Respiratory Drive Brainstem Ventral Root Recording Inspiratory Signal Phrenic Nerve Burst Analysis
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