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电电机组数估计（MUNE）在小鼠后肢肌肉测量复合肌肉动作电位（CMAP）

JoVE 杂志
行为学

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JoVE 杂志行为学

Electrophysiological Motor Unit Number Estimation (MUNE) Measuring Compound Muscle Action Potential (CMAP) in Mouse Hindlimb Muscles

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电电机组数估计（MUNE）在小鼠后肢肌肉测量复合肌肉动作电位（CMAP）

DOI:

10.3791/52899-v

•

09:07 min

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September 25, 2015

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W. David Arnold^2,3, Kajri A. Sheth, Christopher G. Wier, John T. Kissel³, Arthur H. Burghes^3,4, Stephen J. Kolb^3,4

¹Department of Neurology,The Ohio State University Wexner Medical Center, ²Department of Physical Medicine and Rehabilitation,The Ohio State University, ³Department of Neuroscience,The Ohio State University Wexner Medical Center, ⁴Department of Biochemistry and Pharmacology,The Ohio State University Wexner Medical Center

Chapters

00:05Title
02:17Recording Setup and Equipment
03:46Sciatic CMAP
04:44Average Single Motor Unit Potential Size and MUNE Calculation
07:29Results: Example Sciatic CMAP and MUNE
08:21Conclusion

Summary

自动翻译

我们提出精致的协议，允许在电动机单元功能的小鼠体内监测。技术测量复合肌肉动作电位（CMAP）和电动机单元数估计（MUNE）在坐骨神经支配鼠标后肢肌肉进行说明。

Tags

Keywords: Electrophysiology Motor Unit Number Estimation MUNE Compound Muscle Action Potential CMAP Mouse Hindlimb Muscles Neuromuscular System Sciatic Nerve Motor Neurons Motor Unit Potential Submaximal Stimuli Translational Potential

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