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High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes
 

High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes

Article DOI: 10.3791/52718-v • 10:02 min • July 25th, 2015
July 25th, 2015 •
*1,3, *2,3, 1,3
1Department of Neurobiology and Anatomy, West Virginia University, 2Animal Models and Imaging Facility, West Virginia University, 3Mary Babb Randolph Cancer Center, West Virginia University
* These authors contributed equally

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总结概括
Automatic Translation

This protocol describes the application of high-frequency ultrasound (HFUS) for imaging mouse cervical lymph nodes. This technique optimizes visualization and quantification of cervical lymph node morphology, volume and blood flow. Image-guided biopsy of cervical lymph nodes and processing of lymph tissue for histological evaluation is also demonstrated.

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High-frequency Ultrasound Imaging Mouse Cervical Lymph Nodes Non-invasive Method Internal Anatomic Structures Experimental Small Animal Systems B-mode Imaging Power Doppler Circulatory Blood Flow Lymph Node Imaging Mouse Model Systems Detailed Protocol Characterization Of Cervical Lymph Nodes Immunologically-enlarged Cervical Nodes Fine Needle Biopsies Histological Analysis Software-aided Steps Lymph Node Volume Changes Lymph Node Morphology Changes Non-invasive Monitoring
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