This protocol describes a method to quantify mouse sociability. Mice are videotaped as they move and interact in a special cage. Movie processing allows for the automated quantification of sociability with excellent accuracy and reliability.
Varghese, F., Burket, J. A., Benson, A. D., Deutsch, S. I., Zemlin, C. W. Experimental Assessment of Mouse Sociability Using an Automated Image Processing Approach. J. Vis. Exp. (111), e52508, doi:10.3791/52508 (2016).