需要订阅 JoVE 才能查看此. 登录或开始免费试用。
Generación de células T CAR para realizar la terapia adoptiva en el contexto de Glioblastoma estándar de cuidado
21,106 Views
•
12:55 min
•
February 16, 2015
DOI:
Summary
Automatically generated
The lymphodepletive and immunomodulatory effects of chemotherapy and radiation standard of care can be leveraged to enhance the antitumor efficacy of T cell immunotherapy. We outline a method for generating EGFRvIII-specific chimeric antigen receptor (CAR) T cells and administering them in the context of glioblastoma standard of care.
Read Article
Cite this Article
Riccione, K., Suryadevara, C. M., Snyder, D., Cui, X., Sampson, J. H., Sanchez-Perez, L. Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care. J. Vis. Exp. (96), e52397, doi:10.3791/52397 (2015).
Copy